Glucosamine and Chondroitin for Dogs. Why these two ingredients?

If you’ve arrived at this page, chances are you are looking for joint medicine for your dog – something that will help ease the painful symptoms of arthritis, dysplasia, or other join conditions and improve the quality of your dog’s life.

Please read this short intro, which will help you understand a bit more about these substances and what they actually do. Further down the page are my top three recommended products:

Firstly, glucosamine and chondroitin are considerd “neutra-ceutical”, because they are naturally occurring substances found in may parts of the food chain. A bit like vitamins really!

They are available without a prescription, but my advice is to check with your vet first, just in case there are any contra-indications with any other drugs or medication your dog is on.

What are these 2 wonder substances?

Glucosamine provides the foundation to create new cartilage

This is naturally present in a dog’s body already, as a result of internal biochemical reactions. In normal situations the body can make enough to maintain healthy cartilage. However once cartilage starts to wear away through old-age or arthritis, the body can’t make enough on its own anymore, so providing a supplement can be a major benefit.

Chondroitin is a blocking agent to keep out enzymes that destroy the joint cartilage.

Again, chondroitin is already present in healthy cartilage in animals. (Note: It’s usually listed as Chondroitin Sulfate in supplements.)

Are there any side effects?

These products have been used in supplements across Europe for more than 20 years, with little or no recorded symptoms. Occasionally a dog may experience vomiting or diarrhea, as with any medicine or supplement, however if it is given with food or the dosage reduced, these symptoms go away.

How long will my dog need to be on these?

Simply, for the rest of his/her life – if you want to keep symptoms at bay. As soon as they are taken off it, the cartilage degeneration will recur.



glyco-flex III vetrinarian-approved joint support

Form it comes in: Bite Sized Dog Chews

Glyco-Flex III Joint SupportPack contains: 120 chews

Average customer rating: 9.2/10

==> price check it at Amazon


Sometimes a picture says 1000 words, so I am sharing exactly what the manufacturers say about their product (Vetriscience Laboratories). One of the points to not about Glyco-Flex is that vets have been recommending the products for over more than 30 years.

Vetriscience Details about Glyco-Flex

They talk about Green Lipped mussels from New Zealand being a component. This is something I can very much vouch for, as I come from New Zealand originally. The green-lipped mussels are a lot larger in size then most, and are used in many, many health-related products, for humans too!



Features Benefits
Clinically proven For me, this is even more important than the vet recommendations, as it means there is scientific evidence that it works and can be sold for the benefits portrayed. In order for something to be clinically proven, it must go through rigorous testing and trials, so I trust this completely. And just what has been proven? An increase hind leg strength in dogs by up to 41% in 4 weeks – fact.
Recommended by vets I think this is a further endorsement of it working, and the fact these recommendations have been on the go for 30 years plus also gives immense confidence in the product.
Natural Flavors The last thing you want to hear at this stage is that there are all sorts of nasty flavorings used to encourage your dog to eat them. Well, no problem here, as real chicken is used to make these tasty for your dog.


  • These are also available in tablet form if your dog doesn’t take to the treats readily. We used to crush our dog’s up using a mortar and pestle and then stir into his food – he was none the wiser!
  • These can also be used as a bit of a preventative if you have a working or very active dog. It will help provide additional support to these dogs, who place a lot of extra stress on their joints during their lifetime.
  • The packet comes with useful dosage instructions on the reverse, based on your dog’s weight.




Glyco-Flex III Dosage and Ingedients


  • this has some great ingredients in it, and is definitely a great product, but doesn’t contain any chondroitin. Many dogs from joint problems will benefit from both supplements. Our German Shepherd had both and definitely benefited. You can buy it separately, or choose one of the other options below that contain both supplements in the same product.




Form it comes in: Liquid

Bottle contains: 32 fl oz

Average customer rating: 9.2/10

==> price check it at Amazon

TerraMax Pro Liquid Hip & Joint Supplement


A liquid supplement to give extra support to dogs experiencing joint pain and discomfort. A few teaspoons per day can make all the difference to your dog’s quality of life, reducing pain and improving mobility.

Contains both glucosamine and chondroitin sulfate in higher doses than many products on the market, for optimal results in your canine. A liquid form can improve absorption rates, as the digestive system doesn’t have to break down any outer barriers for the body to access the active ingredients.



Features Benefits
Vet Recommended Anything recommended by veterinarians is a good option for your dog. Pointing out the best products available for your dogs, only helps enhance their professional reputation.
Made in the USA There’s no doubt that vitamins and supplements can come from all over the world, but buying from a manufacturer you trust goes a long way to going confident you are actually getting what you think you’re getting! This liquid formula is made using top-quality, high grade ingredients to give you dog the very best.
Money back guarantee The manufacturers are so confident in their product, they give you a 100% satisfaction guarantee. This is fantastic, as it means you can try it out and ensure your dog benefits – if not, you can get your money back. You can’t say fairer than that!


  • This is a really powerful formula – with 1600 mg of Glucosamine Hcl, 1200 mg of Chondroitin Sulfate and 1000 mg of Opti-MSM – all proven to give great results.
  • I personally like that this is in liquid form – it’s much easier to get into a medication routine if it’s linked to feeding times, and this can simply be mixed in with your dog’s meal times. Having a scientific background as well, I also agree that liquid-form medications tend to have higher absorption rates, meaning the ingredients can get to work quicker for you dog.




TerraMax Pro Money Back Guarantee



  • I’m going to mention this, because if you go and read reviews you will see that some dogs don’t like the taste. Let me say first of all, that NO PRODUCT IS EVER GOING TO SUIT 100% OF DOGS. Just like humans, there are subtle physiological differences in dogs – whether due to genetics or environmental factors. this leads me to my own disclaimer at the bottom of this page…



H3 Essentials Hip AND joint supplement

Form it comes in: Soft Chews

Pack contains: 75+ Chews (H3 say 77-78 pieces per pack, and that they tend to overfill, so you may find there are more then 75 – bonus!)

Average customer rating: 8.2/10

==> price check it at Amazon

H3 Essentials Hip & Joint Supplement


A chewable supplement to help joint discomfort, through strengthening cartilage and reducing swelling around the joint. These come in treat from and a chicken flavor, which most dogs seem to love.  The chicken is USA-sourced and falls under the FDA and USDA regulations.

The formula contains 8 ingredients to really benefit your dog. But the main ones are glucosamine and chondroitin – which are the main active ingredients needed for these type of supplements.



Features Benefits
Certified safe by a laboratory I haven’t come across this before, so I’m not sure whether other manufacturers don’t mention it, or whether it is unique to this particular product. Whichever applies, I do see it as an added benefit. If an independent microbiology lab has confirmed there are no nasty bugs present, then you can be confident there is no E. coli etc present in the chews.
Made in the USA Once again, I also see this as a benefit and the manufacturers also mention their lab is subject to strict USA regulations. It’s just that little bit extra confidence that it’s not made overseas with false ingredients!


  • These are very popular, and are actually a number one best seller on Amazon, in their Dog Herbal Supplements category.

H3 Essentials is an Amazon Bestseller




H3 Essentials Hip & Joint Supplement Ingredients



  • These chews don’t contain terribly high dosages of the active ingredients, so beware if you have large dogs you may need to give quite a few!
  • The fact the chews are quite soft means they can be quite crumbly



My own disclaimer: I spend a lot of time researching and reviewing what I think are the best products for the majority of dogs. But I can’t guarantee your own dog will like everything I show case. It’s just like having children – there are some vegetables children will just not eat, because they just don’t like them. So too with dogs – there will always be foods, treats and supplements they just won’t like the taste of. You may need to try something else – there is plenty of choice out there!

If you have anything you would like to add, or have had good results with alternative products, please let me know below. I am happy to add further reviews of high-performing supplements, especially if they give good results for dogs suffering with joint pain. My only condition is they need to contain glucosamine and/or chondroitin to feature here, as these are the ingredients proven to give the most benefit.


2 thoughts on “Glucosamine and Chondroitin for Dogs. Why these two ingredients?

  1. Hi Mara
    Thank you for such an interesting post!
    I’ve never thought about that. Glucosamine and chondroitin work for dogs just like for humans, right?
    It’s just like you say, once cartilage starts to wear away through old-age or arthritis, the body can’t make enough on its own anymore. So too with dogs, that’s why this kind of supplement may be a solution for dogs as well!
    I didn’t know that there was this kind of supplement just for dogs!

    1. Hi Alex,

      Thanks so much for your comments, and yes these two substances are well-known to help out humans too, although in human form! I’m glad you found this useful.


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